AVERON NOTEBOOK TO DISCOVER ACTIONABLE CANCER VULNERABILITIES ENABLED BY NEOMORPH PROTEIN-PROTEIN INTERACTIONS

AVERON notebook to discover actionable cancer vulnerabilities enabled by neomorph protein-protein interactions

Summary: Genomic alterations, such as missense mutations, often lead to the activation of oncogenic pathways and cell transformation by rewiring protein-protein interaction (PPI) networks.Understanding how mutant-directed neomorph PPIs (neoPPIs) drive cancer is vital to developing new personalized clinical strategies.However, the experimental inter

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Adapting to isolation in prison

Concept review This article is Wooden toys of a review nature.It features a presentation and discussion of concepts (including typologies) of adaptation to isolation in prison, which have appeared in the literature over the years, namely concepts by: Leon Rabinowicz, Vladimir Pirozhkov, Donald Clemmer, Gresham Sykes, Erving Goffman, John Irwin, Sta

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